The endocannabinoid system and cancer: therapeutic implication
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چکیده
منابع مشابه
The endocannabinoid system and cancer: therapeutic implication.
The endocannabinoid system is implicated in a variety of physiological and pathological conditions (inflammation, immunomodulation, analgesia, cancer and others). The main active ingredient of cannabis, Δ(9) -tetrahydrocannabinol (Δ(9) -THC), produces its effects through activation of CB(1) and CB(2) receptors. CB(1) receptors are expressed at high levels in the central nervous system (CNS), wh...
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Endogenous arachidonic acid metabolites with properties similar to compounds of Cannabis sativa Linnaeus, the so-called endocannabinoids, have effects on various types of cancer. Although endocannabinoids and synthetic cannabinoids may have pro-proliferative effects, predominantly inhibitory effects on tumor growth, angiogenesis, migration and metastasis have been described. Remarkably, these e...
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Some rights reserved. For more information, please see the item record link above. Title The endocannabinoid system and emotional processing: pathophysiology and therapeutic potential. (2012) 'The endocannabinoid system and emotional processing: pathophysiology and therapeutic potential'.
متن کاملThe endocannabinoid signaling system: pharmacological and therapeutic aspects.
Since the discovery of anandamide in 1992, our knowledge of the endocannabinoid system and its physiological effects has increased greatly, not the least as a result of the availability of compounds affecting endocannabinoid function. In the present review, the pharmacology of the endocannabinoid system is discussed. At present, there are no compounds selectively inhibiting the synthesis of ana...
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INTRODUCTION Dementia currently affects over 35 million people worldwide. The most common form of dementia is Alzheimer's disease (AD). Currently, treatments for AD do not stop or reverse the progression of the disease and they are accompanied by side effects. AREAS COVERED The main features of AD pathology, treatment options currently available, the endocannabinoid system and its functionali...
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ژورنال
عنوان ژورنال: British Journal of Pharmacology
سال: 2011
ISSN: 0007-1188
DOI: 10.1111/j.1476-5381.2011.01327.x